A patient with renal colic was prescribed Nux vomica, Lycopodium, Belladonna and Berberis in rapid succession, each remedy only giving a few minutes relief. Arsenicum album then gave a few days relief before return of the pain, with the patient weakening each day. The symptoms of the patient were then studied in detail, after which sepia was given. The pain disappeared and the patient passed some calculi in her urine. During a discussion on this case Dr.J.T.Kent said that spasms from stones in the ureter cause the pain, and that the remedy that fits the constitution has a tendency to prevent the manufacture of more stones and to relieve the spasm. After the remedy there may be an outpouring of stones. Often Belladonna is indicated, he said, it is not deep enough for the patient but it is complemented frequently by Calcarea carbonica or phosphorica when the picture is of Belladonna. Natrum sulphuricum will often fit the constitution an relieve the acute trouble.