DRUG PROVING (Homoeopathic Pathogenetic Trial)

Drug Proving now termed, as Homoeopathic Pathogenetic Trials (HPT) is a process in which drug substances are put into trial over healthy volunteers and their pathogenetic effects are observed and noted for therapeutic purposes. Therefore, it is the only and unique method, which is based on the nature’s law of cure i.e., Similia Similibus Curentur which states that likes are cured by likes i.e. a drug’s capacity for eradicating a disease, lies in its capacity to produce the same.

Since the discovery of Homoeopathy, the process and methodology of HPTs has improved greatly. In this effort, Council has also developed a plan and protocol of double blind technique in Drug Proving. Process of symptom extraction from HPTs has also been standardized. Success of this methodology can be assessed from the Clinical Verification studies of proving pathogenesis where many symptoms have been repeatedly verified when prescriptions are based upon them. Such symptoms are being reflected in the reports of Clinical Verification programme under individual drugs.

 METHODOLOGY

The drug proving is conducted under Drysdale’s Double Blind Technique where neither the Proving Master nor the Prover knows the name of the drug and its potencies being proved on them. The drug is proved on healthy human beings selected from different regions of the country in order to ascertain whether ecological, socio-economic, climatic, regional factors & food habits, variation in physical constitution of the volunteers affect the drug pathogenesis in any form. A drug is proved at more than one centre. The healthy volunteers are selected on the basis of pre-trial medical examination conducted by Honorary Consultants in the field of Medicine, Psychiatry, Ophthalmology, Otorhino-laryngology, Dermatology, Pathology and Gynaecology (in case of female provers). Drugs are provided to the provers in coded phials and provers are divided into two groups, one receives `placebo’ and other `actual drug’ to distinguish between the false and true symptoms. The Proving Master records the responses of the provers in the prescribed proforma. The data collected during the course of provings is received at the Central Drug Proving-cum-Data Processing Cell at the Headquarters office of the Council, where it is processed, analyzed and compiled and later on published for the use of the profession.

 

 ACHIEVEMENTS

 Drugs Proved so far

1.

 

Abroma augusta folia

2.

Acalypha indica

3.

Acid butyricum

4.

Acorus calamus

5.

Aegle folia

6.

Aegle marmelos

7.

Agave Americana

8.

Alfalfa

9.

Androgrographis paniculata

10.

Aranea diadema

11.

Aranea scinencia

12.

Argemone mexicana

13.

Arsenicum bromicum

14.

Atista indica

15.

Azadirachta indica

16.

Bacopa monniere

17.

Baryta iodata

18.

Bellis perennis

19.

Boerhaavia diffusa

20.

Calotropis gigantea

21.

Carica papaya

22.

Cassia fistula

23.

Cassia sophera

24.

Cephalandra indica

25.

Chelone

26.

Chromo kali sulph

27.

Clerodendron infortunatum

28.

Coleus aromaticus

29.

Cornus circinata

30.

Cup. oxydatum nigrum

31.

Curcuma longa

32.

Cuscuta reflexa

33.

Cynodon dactylon

34.

Embelia ribes

35.

Euphorbia lathyris

36.

Ficus religiosa

37.

Formic acid

38.

Glycyrrhiza glabra

39.

Holarrhena antidysenterica

40.

Hydrocotyle asiatica

41.

Ichthyolum

42.

Juglans regia

43.

Kali muriaticum

44.

Lapis alba

45.

Leucas aspera

46.

Liatris spicata

47.

Magnesia sulphuricum

48.

Mangifera indica

49.

Mimosa humalis

50.

Mygale

51.

Nyctanthes arbortristis

52.

Ocimum canum

53.

Ocimum sanctum

54.

Oxytropis lamberti

55.

Paraffin

56.

Phyllanthus niruri

57.

Pothos foetidus

58.

Pyrus Americana

59.

Rauwolfia serpentina

60.

Ricinus communis

61.

Saraca indica

62.

Senega

63.

Skookum chuck

64.

Staphylococcinum

65.

Tarentula cubensis

66.

Tarentula hispanica

67.

Tela aranea

68.

Terminalia arjuna

69.

Terminalia chebula

70.

Thea chinensis

71.

Theridion

72.

Thymol

73.

Thyroidinum

74.

Tinospora cordifolia

75.

Tribulus terrestris

76.

Tylophora indica

Compilation of 08 drugs has been completed and 06 drugs are under compilation.

Publications :

Proving data of the drugs proved by the Council is published from time to time for the use of the profession in the form of monographs or in Quarterly Bulletin/Indian Journal of Research in Homoeopathy.

  •       Monographs

Monographs of following drugs have been published containing data on Drug Proving, Drug Standardization (involving pharmacognostic, pharmacological and physico-chemical studies) & clinically verified symptoms.

1.

Abroma augusta folia

2.

Kali muriaticum

3.

Cassia sophera

4.

Cynodon dactylon

5.

Aegle folia

6.

Aegle marmelos

7.

Hydrocotyle asiatica

8.

Atista indica

9.

Carica papaya

10.

Terminalia chebula

11

Boerhaavia diffusa

                                               

  •        Books

 

1.            ‘Homoeopathic Drug Provings’

2.            ‘Homoeopathic Drug Proving’, (Volume 2)

3.            Protocol on Homoeopathic Pathogenetic Trial (Drug Proving) 2007

 

·        Articles on other drugs proved by the Council and published in the Bulletin/ Indian Journal of Research in Homoeopathy. :

Sl. No.

Name of the drugs

No.& Issue of Quarterly Bulletin/IJRH.

1.

Cassia sophera

Q. B. Vol. 2  (2),   1980

2.

Baryta iodatum

Q. B. Vol. 2  (3),   1980

3.

Cynodon dectylon

Q. B. Vol. 2  (4),   1980

4.

Kali muriaticum

Q. B. Vol. 3  (1),   1981

5.

Formic acidum

Q. B. Vol. 7  (4),   1985

6.

Cuprum oxydatum nigrum

Q. B. Vol. 7 (1-4), 1985

7.

Aegle folia

Q. B. Vol.9  (3-4), 1987(Drug Proving Special I)

8.

Aranea diadema

-do-

9.

Boerhaavia diffusa

-do-

10.

Hydrocotyle asiatica

-do-

11.

Mygale

-do-

12.

Tarentula cubensis

-do-

13.

Tarentula hispanica

-do-

14.

Aegle marmelos

Q. B. Vol. 12 (1-2), 1990 (Drug Proving Special II)

15.

Aranea scinencia

-do-

16.

Atista indica

-do-

17.

Cassia fistula

-do-

18.

Tela aranea

-do-

19.

Thea chinensis

-do-

20.

Azadirachta indica

Q. B. Vol. 13 (1-2), 1991

21.

Tylophora indica

-do-

22.

Curcuma longa

-do-

23.

Holarrhena antidysenterica

Q. B. Vol.15 (1-2), 1993

24.

Terminalia arjuna

-do-

25.

Terminalia chebula

-do-

26.

Embelia ribes

Q. B. Vol. 17 (3-4), 1995

27.

Lapis alba

-do-

28.

Thymol

-do-

29.

Acalypha indica

Q. B. Vol. 18 (1-2), 1996

30.

Theridion

-do-

31.

Mag. sulph

Q. B. Vol. 19 (1-2), 1997(Drug Proving Special-III)

32.

Glycyrrhiza glabra

-do-

33.

Mangifera indica

-do-

34.

Phyllanthus niruri

-do-

35.

Carica papaya

-do-

36.

Nyctanthes arbortristis

-do-

37.

Terminalia chebula

-do-

38.

Acid butyricum

Q. B. Vol. 24 (3-4), 2003(Drug Proving Special-IV)

39.

Arsenicum bromatum

-do-

40.

Chromo kali sulph

-do-

41.

Euphorbia lathyris

-do-

42.

Ocimum can

-do-

43.

Oxytropis lamberti

-do-

44.

Rauwolfia serpentina

-do-

45.

Ricinus communis

-do-

46.

Staphylococcinum

-do-

47.

Tribulus terrestris

-do-

48.

Alfalfa

Q. B. Vol. 26 (2), 2004

49.

Bellis perennis

Q. B. Vol. 26 (3), 2004

50.

Calotropis gigantea

Q. B. Vol. 26 (4), 2004

51.

Ichthyolum

Q. B. Vol. 27 (1), 2005

52.

Pyrus americana           

Q. B. Vol. 27 (2), 2005

53.

Tarentula hispanica

Q. B. Vol. 27 (3), 2005

54.

Agave americana

IJRH, Vol. 1, No. 1 2007

 

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