A case is related of an eleven year old boy who suffers severe asthmatic attacks usually during the night. Following detailed case analysis an M potency of Natrum sulphuricum is prescribed on the basis of seven key symptoms. This is effective for a while then the attacks resume. Arsenicum album, which was also indicated in some of the symptoms, is then administered in a Q potency. He does well on this for around four months apart from a skin eruption and a diarrhoea attack but no remedy is administered for these. The boy then comes down with a cough, coryza and sneezing and Natrum sulphuricum M is administered with success and is repeated at long intervals and increasing potency.