Objectives: The objectives of the study were to determine therapeutic efficacy of homoeopathic medicines in the management of bronchial asthma and to identify reliable indications of the effective medicines, most useful potencies, frequency of administration, and their relationship with other medicines. The objectives also included determining the efficacy of homoeopathic medicines to alleviate acute exacerbation of asthma and to prevent further progression of disease by controlling recurrent attacks.
Methods: It was a multi-centric observational study (Open clinical trial) carried out by Central Council for Research in Homoeopathy at its five research institutes/units from the year 1978 to 2003. Out of 2641 bronchial asthma patients enrolled, 2107 patients were followed up regularly. The detailed case recording was done for each case and the medicine (similimum) was prescribed according to the principles of Homoeopathy. During acute attacks, medicines were selected on the basis of presenting symptoms while during asymptomatic phase, medicines were selected on constitutional basis. Mother tinctures of certain medicines were used to check acute attacks of asthma.
Results: Out of 2107 cases followed up, 52 patients were cured and 1822 cases improved in varying degrees: marked improvement in 856 cases, moderate improvement in 444 cases and mild improvement in 522 cases. Improved cases showed less frequent acute exacerbations and decreased intensity and duration of subsequent attacks of asthma. Out of these 233 cases did not improve. Arsenicum album was seen to be the most effective and most frequently indicated medicine in the treatment of asthma as it alone improved 933 cases out of 1042 cases it was prescribed. Other medicines found effective were Hepar sulphuris (n=51), Kali carbonicum (n=83), Lycopodium clavatum (n=60), Natrum sulphuricum (n=78), Phosphorus (n=34) and Pulsatilla nigricans (n=63). Viburnum opulum mother tincture was found effective during acute attacks of asthma (n=29).
Conclusion: The outcome of the study shows that homoeopathic medicines are effective in managing acute attacks of bronchial asthma as well as in controlling recurrent attacks of asthma. A group of most effective medicines in asthma were evolved and their most reliable indications were deduced in this study. The other objectives of the study that included most useful potencies of medicines, their frequency of administration and relationship with other medicines could not be achieved. Now Council has taken up a multicentric study on Chronic bronchitis with pulmonary function test markers since 2005.
Regional Research Institute, Gudivada, Andhra Pradesh
G. C. Sehgal and Bhawan Singh,
Clinical Research Unit, Patiala, Punjab
V. K. Khanna and A.K.Vichitra,
Regional Research Institute, New Delhi
S. R. Sharma and Bindu sharma,
Regional Research Institute, Shimla
E. C. Thomas, T. N. S. Kurup, K. Raju, B. Indira and Papula Prasad,
Clinical Research Unit, Udupi