Medical research is a broad discipline. The era of medicine in Homoeopathy begins with Hahnemann, the founder of Homoeopathy. Among all the different types of research, clinical trials form a key step to prove the safety and efficacy of the therapy and form the bridge between research and clinical practice. Clinical Research plays a major role in the development of medicine. It has been more so in case of Homoeopathy wherein symptomatic data obtained by means of proving (experimentation) of drugs on healthy human beings, need to be repeatedly verified on patients in the clinics to be valid before it forms part of the Homoeopathic materia medica. It also helps in the elucidation of fundamental principles and their application in the treatment of various diseases. It has therefore, remained an important research activity of the Council ever since its inception in 1978.

The main objectives of CCRH in Clinical research are clinical confirmation of drug-pathogenesis; elicitation of new clinical symptoms; evaluation of clinical drug pictures; classification of various complexions, temperaments and constitutions, and to evaluate action of homoeopathic drugs on any given pathological conditions. The programmes were initiated with pre designed protocols and laboratory parameters for outcome assessment on scientific lines.

Some of the clinical studies undertaken at the time of inception of the Council were continued for over a decade due to the prevalence of diseases in those areas. All studies undertaken during 1979 were concluded except diseases of national importance as per the decision of Scientific Advisory Committee (SAC) in 2003, so that new evidence based studies could be initiated. The outcome of some of these studies have been published in Clinical Research Series I, II & III. These are prized publications and can be obtained from CCRH. The positive gain of these findings is that the profession will now have a smaller number of homoeopathic medicines to refer to for a particular disease and the scope of conducting further research in these diseases.

On the basis of outcome of these studies the Council has undertaken further multicentric clinical studies to ascertain therapeutic utility of a smaller group of medicines on the Protocols developed in consultation with the experts in respective fields from All India Institute of Medical Sciences (AIIMS), Indian Council of Medical Research (ICMR), National Institute of Communicable Diseases (NICD), National AIDS Control Organization (NACO) and eminent homeopathic Educators and Researchers. The Council undertook these studies for both general and tribal areas in 2005 at its Institutes/Units on the same protocols. These studies have been concluded. These manuscripts on for of these diseases have been published in international journals. The council has also initiated 7 RCTs in June 2010